Article
Poor correspondence between predicted and experimental binding of peptides to class I MHC molecules.
Tissue antigens - 1 Jun 2000
Andersen M H, Tan L, Søndergaard I, Zeuthen J, Elliott T, Haurum J S
Abstract excerpt
Naturally processed peptides presented by class I major histocompatibility complex (MHC) molecules display a characteristic allele specific motif of two or more essential amino acid side chains, the so-called peptide anchor residues, in the context of an 8-10 amino acid long peptide. Knowledge of the peptide binding motif of individual class I MHC molecules permits the selection of potential peptide antigens from...
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