Article
Evaluation of different generic in silico methods for predicting HLA class I binding peptide vaccine candidates using a reverse approach.
Amino acids - 1 Nov 2010
Gowthaman Uthaman, Chodisetti Sathi Babu, Parihar Pankaj, Agrewala Javed N
Abstract excerpt
Since CD8+ T cell response is crucial to combat intracellular infections and cancer, identification of class I HLA binding peptides is of immense clinical value. The experimental identification of such peptides is protracted and laborious. Exploiting in silico tools to discover such peptides is an attractive alternative. However, this approach needs a thorough assessment before its elaborate application. We have...
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