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Article

Predicting MHC class I epitopes in large datasets.

BMC bioinformatics - 17 Feb 2010

Roomp Kirsten, Antes Iris, Lengauer Thomas

Abstract excerpt

BACKGROUND: Experimental screening of large sets of peptides with respect to their MHC binding capabilities is still very demanding due to the large number of possible peptide sequences and the extensive polymorphism of the MHC proteins. Therefore, there is significant interest in the development of computational methods for predicting the binding capability of peptides to MHC molecules, as a first step towards...

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Identifiers

PMID: 20163709
DOI: 10.1186/1471-2105-11-90
PMCID: PMC2836306

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