Article
The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea.
Gut - 1 Aug 2000
Kim H C, Wheeler J M, Kim J C, Ilyas M, Beck N E, Kim B S, Park K C, Bodmer W F
Abstract excerpt
INTRODUCTION: Germline mutations in E-cadherin (CDH1) have been reported in families with early onset, diffuse gastric cancer. More recently, mutations in CDH1 have been described in colorectal cancer cell lines. AIMS: We have investigated if germline mutations in CDH1 occur among different group...
Topics
- Adolescent
- Adult
- Aged
- Cadherins
- Case-Control Studies
- Child
- Child, Preschool
- Colorectal Neoplasms
- Female
- Genotype
- Germ-Line Mutation
- Humans
- Infant
- Infant, Newborn
- Male
- Middle Aged
- Mutation, Missense
- Neoplasm Proteins