Article
Frequency of CDH1 germline mutations in gastric carcinoma coming from high- and low-risk areas: metanalysis and systematic review of the literature.
BMC cancer - 6 Jan 2012
Corso Giovanni, Marrelli Daniele, Pascale Valeria, Vindigni Carla, Roviello Franco
Abstract excerpt
BACKGROUND: The frequency of E-cadherin germline mutations in countries with different incidence rates for gastric carcinoma has not been well established. The goal of this study was to assess the worldwide frequency of CDH1 germline mutations in gastric cancers coming from low- and high-risk are...
Topics
- Antigens, CD
- Cadherins
- Carcinoma
- Gene Frequency
- Genetic Predisposition to Disease
- Germ-Line Mutation
- Humans
- Mutation Rate
- Stomach Neoplasms