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Article

Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer.

Human molecular genetics - 1 Apr 1999

Richards F M, McKee S A, Rajpar M H, Cole T R, Evans D G, Jankowski J A, McKeown C, Sanders D S, Maher E R

Abstract excerpt

Inherited mutations in the E-cadherin gene ( CDH1 ) were described recently in three Maori kindreds with familial gastric cancer. Familial gastric cancer is genetically heterogeneous and it is not clear what proportion of gastric cancer susceptibility in non-Maori populations is due to germline CDH1 mutations. Therefore, we screened eight familial gastric cancer kindreds of British and Irish origin for germline...

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Source

Identifiers

PMID: 10072428
DOI: 10.1093/hmg/8.4.607

Genes

CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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