Article
Detection of CDH1 gene variants in early-onset diffuse gastric cancer in Chinese patients.
Clinical laboratory - 1 Jan 2014
Yanjun Xu, Wenming Cao, Lisha Ying, Qi Xu, Jianmin Guo, Xinbao Wang, Xiangdong Cheng, Jieer Ying
Abstract excerpt
BACKGROUND: The type and frequency of E-cadherin (CDH1) germline variants in China for the early-onset diffuse gastric cancer (EODGC) has not been well established. Our study tend to screen and characterize germline variants for CDH1 gene in EODGC patients and in general population in China. METHODS: Peripheral blood samples were collected from 57 EODGC patients (age ≤ 40 years) who underwent resection surgery...
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