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Article

Inactivation of the PTEN gene by mutation, exonic deletion, and loss of transcript in human oral squamous cell carcinomas.

International journal of oncology - 1 Nov 2002

Shin Ki-Hyuk, Kim Jin-Man, Rho Kyong Su, Park Kyung-Hee, Oh Ju-Eun, Min Byung-Moo

Abstract excerpt

PTEN, a tumor suppressor gene, has been found to be inactivated by structural abnormalities or epigenetic changes in several types of human cancers. Recently, several studies have also suggested the possibility that the PTEN gene is a target of genomic instability in human cancers displaying microsatellite instability (MSI). To investigate the role of PTEN in human oral squamous cell carcinomas, we screened the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12370746

Genes

PTEN
AGA
GAA
GCA
GCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Inactivation of the PTEN gene by mutation, exonic deletion, and loss of transcript in human oral squamous cell carcinomas.PMID 12370746Read ↗

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Homozygous deletion of the PTEN tumor-suppressor gene is not a feature in oral squamous cell carcinoma.Semantic proximity Read ↗

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