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Article

PTEN expression and methylation status in oral squamous cell carcinoma.

Oncology reports - 1 Jun 2008

Kurasawa Yoshinori, Shiiba Masashi, Nakamura Megumi, Fushimi Kazuaki, Ishigami Takashi, Bukawa Hiroki, Yokoe Hidetaka, Uzawa Katsuhiro, Tanzawa Hideki

Abstract excerpt

PTEN is a tumor suppressor gene located on chromosome10q23.3. In addition to genetic mutations and deletions, the down-regulation of PTEN has been found in various malignant tumors. However, little is known about the profile of PTEN gene in oral carcinomas. In this study, the expression profiles and genetic alterations of PTEN were examined in 113 oral squamous cell carcinoma (OSCC) cases and 9 OSCC-derived cell...

Read the complete abstract on PubMed

Topics

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Share to Carcinoma, Squamous Cell
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Gene Expression Regulation, Neoplastic

Share to Mouth Neoplasms

Share to Polymorphism, Single-Stranded Conformational

Share to PTEN Phosphohydrolase

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 18497947

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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