Article
Allele frequency of human endothelial nitric oxide synthase gene polymorphism in abdominal aortic aneurysm.
Internal medicine (Tokyo, Japan) - 1 Jul 2000
Kotani K, Shimomura T, Murakami F, Ikawa S, Kanaoka Y, Ohgi S, Adachi K, Nanba E
Abstract excerpt
OBJECTIVE: This study was performed to examine the role of the endothelial constitutive NO synthase (ecNOS) gene in patients with abdominal aortic aneurysm (AAA). METHODS: We determined the distributions of polymorphism in intron 4 of the ecNOS (ecNOS4) gene, amplified by polymerase chain reaction, and compared the allele frequencies between subjects with abdominal aortic aneurysms (AAAs) and healthy individuals....
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