Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations of Genes for Killer Cell Immunoglobulin-like Receptors and Their Human Leukocyte Antigen-A/B/C Ligands with Abdominal Aortic Aneurysm.

Cells - 30 Nov 2021

Dubis Joanna, Niepiekło-Miniewska Wanda, Jędruchniewicz Natalia, Sobczyński Maciej, Witkiewicz Wojciech, Zapotoczny Norbert, Kuśnierczyk Piotr

Abstract excerpt

Abdominal aortic aneurysm (AAA) is an immune-mediated disease with a genetic component. The multifactorial pathophysiology is not clear and there is still no pharmacotherapy to slow the growth of aneurysms. The signal integration of cell-surface KIRs (killer cell immunoglobulin-like receptors) with HLA (ligands, human leukocyte class I antigen molecules) modulates the activity of natural killer immune cells. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic Aneurysm, Abdominal
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Artery Disease

Share to Genetic Association Studies

Share to Haplotypes

Share to HLA Antigens

Share to Ligands

Share to Receptors, KIR

Source

Open in PubMed Open full text

Identifiers

PMID: 34943866
DOI: 10.3390/cells10123357
PMCID: PMC8699266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations of Genes for Killer Cell Immunoglobulin-like Receptors and Their Human Leukocyte Antigen-A/B/C Ligands with Abdominal Aortic Aneurysm.PMID 34943866Read ↗

Genome wide association studies of abdominal aortic aneurysms-biological insights and potential translation applications.Semantic proximity Read ↗

Assessing the causal relationship between circulating immune cells and abdominal aortic aneurysm by bi-directional Mendelian randomization analysis.Semantic proximity Read ↗

Genes and abdominal aortic aneurysm.Semantic proximity Read ↗

Immunohistochemical Analysis of the Natural Killer Cell Cytotoxicity Pathway in Human Abdominal Aortic AneurysmsSemantic proximity Read ↗

Correlation Between ABCA1 Gene Polymorphism and aopA-I and HDL-C in Abdominal Aortic Aneurysm.Semantic proximity Read ↗

Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysmsSemantic proximity Read ↗

TLR2 2029C/T and TLR3 1377C/T and -7C/A Polymorphisms Are Associated with the Occurrence of Abdominal Aortic Aneurysm.Semantic proximity Read ↗

A variant in LDLR is associated with abdominal aortic aneurysm.Semantic proximity Read ↗

Association of the TGF-beta receptor genes with abdominal aortic aneurysm.Semantic proximity Read ↗

Differential gene expression in human abdominal aortic aneurysm and aortic occlusive diseaseSemantic proximity Read ↗

Association between gene polymorphism of inflammatory factors, thrombogenic factors, and stress-related proteins and abdominal aortic aneurysm: A meta-analysis and systematic review.Semantic proximity Read ↗

Abdominal Aortic Aneurysm Genetic Associations: Mostly False? A Systematic Review and Meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.