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Endothelial nitric oxide synthase gene intron 4 polymorphism in patients with end-stage renal disease.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 2004

Buraczynska Monika, Ksiazek Piotr, Zaluska Wojciech, Nowicka Teresa, Ksiazek Andrzej

Abstract excerpt

BACKGROUND: Nitric oxide (NO) synthesized by endothelial cell NO synthase (ecNOS) is a potent regulator of intrarenal haemodynamics. A polymorphism in intron 4 of the ecNOS gene is a candidate gene in cardiovascular and renal diseases. We investigated a potential involvement of this polymorphism in chronic renal failure. METHODS: We performed a case-control study involving 706 patients with end-stage renal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15299097
DOI: 10.1093/ndt/gfh077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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