Article
The influence of COX-2 single nucleotide polymorphisms on abdominal aortic aneurysm development and the associated inflammation.
Angiology - 1 Jan 2000
Badger Stephen A, Soong Chee V, Young Ian S, McGinty Ann, Mercer Caroline, Hughes Anneq E
Abstract excerpt
INTRODUCTION: Cyclooxygenase (COX)-2 influences cardiovascular disease and serum concentration of high-sensitivity C-reactive protein (hsCRP). The study purpose was to determine the influence of single nucleotide polymorphisms (SNPs) of the COX-2 gene on abdominal aortic aneurysm (AAA) development and serum hsCRP concentrations. PATIENTS AND METHODS: Patients with AAA and disease-free controls were recruited....
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