Article
Serum lipoprotein profile and APOE genotype in Alzheimer's disease.
Journal of neural transmission. Supplementum - 1 Jan 2007
Cagnin A, Zambon A, Zarantonello G, Vianello D, Marchiori M, Mercurio D, Miccichè F, Ermani M, Leon A, Battistin L
Abstract excerpt
Alterations in cholesterol homeostasis are associated with Alzheimer's disease (AD). The role played by specific fractions of serum lipoproteins in modifying the risk of AD, and the interaction with APOE genotype has not yet been investigated. We studied serum lipoprotein profiles using a gradient-density ultracentrifugation method in a cohort of late-onset sporadic AD patients without cerebrovascular lesions and...
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