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Article

Influence of APOE4 genotype on PCSK9-lipids association in cerebrospinal fluid and serum of patients in the Alzheimer's disease continuum.

Journal of Alzheimer's disease : JAD - 1 Nov 2024

Papotti Bianca, Palumbo Marcella, Adorni Maria Pia, Elviri Lisa, Chiari Annalisa, Tondelli Manuela, Bedin Roberta, Baldelli Enrica, Lancellotti Giulia, Lupo Maria Giovanna, Ferri Nicola, Bertolotti Marco, Bernini Franco, Mussi Chiara, Zimetti Francesca

Abstract excerpt

BACKGROUND: Alterations in factors involved in cholesterol homeostasis are critical in Alzheimer's disease (AD), but the stage of occurrence, their specific association, and a possible relationship with the APOE4 genotype are not clarified. OBJECTIVE: We aimed to quantify and correlate specific lipid factors in patients with different degrees of cognitive decline, namely patients with AD and patients with mild...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39497318
DOI: 10.1177/13872877241284213

Genes

PCSK9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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