Article
The crystal structure of NusB from Mycobacterium tuberculosis.
Nature structural biology - 1 Jun 2000
Gopal B, Haire L F, Cox R A, Jo Colston M, Major S, Brannigan J A, Smerdon S J, Dodson G
Abstract excerpt
Both prokaryotes and eukaryotes regulate transcription through mechanisms that suppress termination signals. An antitermination mechanism was first characterized in bacteriophage lambda. Bacteria have analogous machinery that regulates ribosomal RNA transcription and employs host factors, called the N-utilizing (where N stands for the phage lambda N protein) substances (Nus), NusA, NusB, NusE and NusG. Here we...
Topics
- Amino Acid Motifs
- Amino Acid Sequence
- Bacterial Proteins
- Binding Sites
- Conserved Sequence
- Crystallography, X-Ray
- Dimerization
- Escherichia coli Proteins
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Mycobacterium tuberculosis
- Phosphates
- Protein Binding