Article
Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex.
Molecular cell - 26 Dec 2008
Luo Xiao, Hsiao He-Hsuan, Bubunenko Mikhail, Weber Gert, Court Donald L, Gottesman Max E, Urlaub Henning, Wahl Markus C
Abstract excerpt
Protein S10 is a component of the 30S ribosomal subunit and participates together with NusB protein in processive transcription antitermination. The molecular mechanisms by which S10 can act as a translation or a transcription factor are not understood. We used complementation assays and recombineering to delineate regions of S10 dispensable for antitermination, and determined the crystal structure of a...
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