Article
The structure of the transcriptional antiterminator NusB from Escherichia coli.
Nature structural biology - 1 Jun 2000
Altieri A S, Mazzulla M J, Horita D A, Coats R H, Wingfield P T, Das A, Court D L, Byrd R A
Abstract excerpt
We have determined the solution structure of NusB, a transcription antitermination protein from Escherichia coli. The structure reveals a novel, all alpha-helical protein fold. NusB mutations that cause a loss of function (NusB5) or alter specificity for RNA targets (NusB101) are localized to surface residues and likely affect RNA-protein or protein-protein interactions. Residues that are highly conserved among...
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