Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination.

Nucleic acids research - 1 Sept 2011

Stagno Jason R, Altieri Amanda S, Bubunenko Mikhail, Tarasov Sergey G, Li Jess, Court Donald L, Byrd R Andrew, Ji Xinhua

Abstract excerpt

Processive transcription antitermination requires the assembly of the complete antitermination complex, which is initiated by the formation of the ternary NusB-NusE-BoxA RNA complex. We have elucidated the crystal structure of this complex, demonstrating that the BoxA RNA is composed of 8 nt that are recognized by the NusB-NusE heterodimer. Functional biologic and biophysical data support the structural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Escherichia coli Proteins
Share to Genetic Complementation Test

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Protein Multimerization

Share to Ribosomal Proteins

Share to RNA-Binding Proteins

Share to RNA, Double-Stranded

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 21652641
DOI: 10.1093/nar/gkr418
PMCID: PMC3177189

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination.PMID 21652641Read ↗

Structural and functional analyses of the transcription-translation proteins NusB and NusE.Semantic proximity Read ↗

Bacteriophage lambda N-dependent transcription antitermination. Competition for an RNA site may regulate antitermination.Semantic proximity Read ↗

Fine tuning of the E. coli NusB:NusE complex affinity to BoxA RNA is required for processive antitermination.Semantic proximity Read ↗

The nut site of bacteriophage lambda is made of RNA and is bound by transcription antitermination factors on the surface of RNA polymerase.Semantic proximity Read ↗

A protein-RNA interaction network facilitates the template-independent cooperative assembly on RNA polymerase of a stable antitermination complex containing the lambda N protein.Semantic proximity Read ↗

Assembly of the N-dependent antitermination complex of phage lambda: NusA and RNA bind independently to different unfolded domains of the N protein.Semantic proximity Read ↗

Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex.Semantic proximity Read ↗

The alpha subunit of E. coli RNA polymerase activates RNA binding by NusA.Semantic proximity Read ↗

The alpha subunit of RNA polymerase and transcription antitermination.Semantic proximity Read ↗

New discoveries linking transcription to DNA repair and damage tolerance pathways.Semantic proximity Read ↗

Structure and semi-sequence-specific RNA binding of Nrd1.Semantic proximity Read ↗

The antiterminator NusB enhances termination at a sub-optimal Rho site.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.