Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 gene mutation and protein expression in operable non-small cell lung cancer in Poland.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Apr 2000

Niklinska W, Burzykowski T, Chyczewski L, Rusin M R, Furman M, Laudanski J, Chyczewska E, Sulik M, Niklinski J

Abstract excerpt

We investigated the association of p53 abnormalities (gene mutations by DNA sequencing and protein over-expression by immunostaining) with clinical data and prognosis in 74 patients with resected non-small cell lung cancer (NSCLC). DNA analysis of exons 5-8 of the p53 gene showed 34 mutations in 74 resected primary NSCLC (45.9%). Immunohistochemical study of the p53 protein revealed that 41 of 74 (55.4%) samples...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Neoplasm Proteins

Share to Neoplasm Staging

Share to Odds Ratio

Share to Poland

Share to Survival Rate

Source

Identifiers

PMID: 10830574
DOI: 10.1097/00008469-200004000-00003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 gene mutation and protein expression in operable non-small cell lung cancer in Poland.PMID 10830574Read ↗

Strong association between P53 protein accumulation, serum antibodies and gene mutation in non-small cell lung cancer.Semantic proximity Read ↗

Prognostic significance of p53 alterations in patients with non-small cell lung cancer: a meta-analysis.Semantic proximity Read ↗

p53 immunostaining is correlated with reduced survival and is not correlated with gene mutations in resected pulmonary large cell carcinomas.Semantic proximity Read ↗

p53 nuclear immunostaining and gene mutations in non-small-cell lung cancer and their effects on patient survival.Semantic proximity Read ↗

Correlation between the status of the p53 gene and survival in patients with stage I non-small cell lung carcinoma.Semantic proximity Read ↗

Significance of TP53 mutations as predictive markers of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer.Semantic proximity Read ↗

p53 exon 5 mutations as a prognostic indicator of shortened survival in non-small-cell lung cancer.Semantic proximity Read ↗

p53 immunostaining positivity is associated with reduced survival and is imperfectly correlated with gene mutations in resected non-small cell lung cancer. A preliminary report of LCSG 871.Semantic proximity Read ↗

TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value.Semantic proximity Read ↗

Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer.Semantic proximity Read ↗

p53 null mutations undetected by immunohistochemical staining predict a poor outcome with early-stage non-small cell lung carcinomas.Semantic proximity Read ↗

p53 expression in non small cell lung cancer: clinical and biological correlations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.