Article
Prognostic significance of mutant p53 protein, P-glycoprotein and glutathione S-transferase-pi in patients with unresectable non-small cell lung cancer.
Anticancer research - 1 Jan 2000
Miyatake Kazuyo, Gemba Kenichi, Ueoka Hiroshi, Nishii Kenji, Kiura Katsuyuki, Tabata Masahiro, Shibayama Takuo, Takigawa Nagio, Kawaraya Masashi, Tanimoto Mitsune
Abstract excerpt
BACKGROUND: The prognostic significance of mutant p53 protein, p-glycoprotein (P-gp) and glutathione S-transferase-pi (GST-pi) in patients with unresectable non-small cell lung cancer (NSCLC) has not been established. MATERIALS AND METHODS: We performed immunohistochemical staining of p53, P-gp and GST-pi using transbronchial biopsy specimens obtained from previously untreated NSCLC patients. RESULTS: Of 45...
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