p53 expression in non small cell lung cancer: clinical and biological correlations.

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Article

p53 expression in non small cell lung cancer: clinical and biological correlations.

Anticancer research - 1 Jan 2000

Fontanini G, Bigini D, Vignati S, Macchiarini P, Pepe S, Angeletti C A, Pingitore R, Squartini F

Abstract excerpt

p53 is a tumor suppressor gene, located in the short arm of chromosome 17, which encodes for a nuclear protein involved in the control of cellular growth. Mutations in p53 gene are the most common genetic alterations in a several human cancers, including Non Small Cell Lung Cancer (NSCLC). Howeve...

Topics

Antigens, Neoplasm
Carcinoma, Non-Small-Cell Lung
Cell Nucleus
Flow Cytometry
Genes, p53
Humans
Ki-67 Antigen
Lung Neoplasms
Middle Aged
Mutation
Neoplasm Proteins
Nuclear Proteins
Ploidies
Proliferating Cell Nuclear Antigen
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 8100413

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8100413-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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