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Article

Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease.

Neuroscience letters - 7 Jul 2000

Bhojak T J, DeKosky S T, Ganguli M, Kamboh M I

Abstract excerpt

Alzheimer's disease (AD) is a complex multi-factorial disease with the involvement of several possible genes. The apolipoprotein E*4 (APOE*4) allele of the known susceptibility gene, APOE, is neither necessary nor sufficient to cause AD. This has prompted the search for other candidate genes associated with the risk of AD. Cathepsin D (Cat D) is an intracellular aspartyl protease that has been reported to have in...

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Source

Identifiers

PMID: 10869806
DOI: 10.1016/s0304-3940(00)01185-x

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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