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Article

The genetic association between Cathepsin D and Alzheimer's disease.

Neuroscience letters - 28 Jul 2000

Crawford F C, Freeman M J, Schinka J, Abdullah L I, Richards D, Sevush S, Duara R, Mullan M J

Abstract excerpt

The aspartyl protease Cathepsin D has previously been suggested to play a role in the Alzheimer's disease (AD) process because of its ability to cleave the beta-amyloid precursor protein and the possibility that it may be one of the 'secretase' enzymes. A functional C-->T polymorphism in the Cath...

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Identifiers

PMID: 10899409
DOI: 10.1016/s0304-3940(00)01260-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10899409-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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