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Article

Association study of cathepsin D gene polymorphism in Iranian patients with sporadic late-onset Alzheimer's disease.

Dementia and geriatric cognitive disorders - 1 Jan 2014

Sayad Azadeh, Noruzinia Mehrdad, Zamani Mahdi, Harirchian Mohammad Hossein, Kazemnejad Anoushiravan

Abstract excerpt

One of the most prevalent forms of dementia is Alzheimer's disease (AD). Complex inheritance and multifactorial patterns of late-onset AD (LOAD) along with its heterogeneity are due to the presence of different AD-predisposing genes with different influence on disease development among various populations. A key event in the pathogenesis of AD is the deposition of β-amyloid peptide, which is derived from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24281128
DOI: 10.1159/000347128

Genes

CTSD
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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