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Article

Contribution of apolipoprotein E and cathepsin D genotypes to the familial aggregation of Alzheimer's disease.

Dementia and geriatric cognitive disorders - 1 Jan 2004

Heun Reinhard, Ptok Ursula, Kölsch Heike, Maier Wolfgang, Jessen Frank

Abstract excerpt

OBJECTIVE: The familial aggregation of late-onset Alzheimer's disease (AD) might be caused by the clustering of genetic risk factors in families. This study investigates the influence of variants of candidate genes on the familial aggregation of AD. METHODS: The occurrence of AD was examined in 1,420 first-degree relatives of 70 AD patients and 144 nondemented controls classified by the presence of AD and...

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Identifiers

PMID: 15211070
DOI: 10.1159/000079195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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