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Article

Search for genetic factors associated with susceptibility to multiple sclerosis.

Annals of the New York Academy of Sciences - 1 May 2006

Forte Giusi Irma, Ragonese Paolo, Salemi Giuseppe, Scola Letizia, Candore Giuseppina, D'Amelio Marco, Crivello Antonio, Di Benedetto Norma, Nuzzo Domenico, Giacalone Antonio, Lio Domenico, Caruso Calogero

Abstract excerpt

Multiple sclerosis (MS) is a cell-mediated autoimmune disease characterized by type-1 cytokine production. Environmental and individual genetic background might influence this response particularly in cytokine gene polymorphisms. We evaluated whether polymorphisms of interleukin (IL)-10, IL-12, and tumor necrosis factor (TNF)-alpha genes, which might play a role in MS pathogenesis, are associated with MS...

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Identifiers

PMID: 16803996
DOI: 10.1196/annals.1354.034

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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