Article
Interleukin 18 receptor 1 expression distinguishes patients with multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Sept 2010
Gillett Alan, Thessen Hedreul Melanie, Khademi Mohsen, Espinosa Alexander, Beyeen Amennai D, Jagodic Maja, Kockum Ingrid, Harris Robert A, Olsson Tomas
Abstract excerpt
Definition of dysregulated immune components in multiple sclerosis may help in the identification of new therapeutic targets. Deviation of the interleukin 18 receptor 1 (IL18R1) is of particular interest since the receptor is critical for experimental neuroinflammation. The objective of this study was to determine whether expression of IL18R1 varies between multiple sclerosis patients and controls, and to test...
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