Article
The association between genetic polymorphisms in CYP19 and breast cancer risk in Korean women.
Oncology reports - 1 Sept 2009
Kim Ji Young, Lee Chang Suk, Kim Hye Ok, Jo Yong Hwa, Lee Juhie, Jung Min Hyung, Baik Hyung Hwan, Choe Wonchae, Kang Insug, Yoon Kyung-Sik
Abstract excerpt
Aromatase encoding by the CYP19 gene catalyzes the conversion of androgens to estrogens. In order to determine if polymorphisms of the CYP19 gene are associated with breast cancer risk, we analyzed the frequency of tetranucleotide (TTTA) tandem repeats and a 3-bp insertion (I)/deletion (D) polymorphism in intron 4 of the CYP19 gene in genomic DNA from 70 Korean breast cancer patients and 102 age-matched, healthy...
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