Article
Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk.
Carcinogenesis - 1 Feb 2000
Healey C S, Dunning A M, Durocher F, Teare D, Pharoah P D, Luben R N, Easton D F, Ponder B A
Abstract excerpt
The aromatase enzyme catalyses the conversion of androgens to oestrogens in the oestrogen biosynthesis pathway. Because increased exposure to oestrogens is considered to be a risk factor for breast cancer, the human aromatase gene (CYP19) is a plausible candidate for low penetrance breast cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
