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Article

Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.

Nucleic acids research - 1 Aug 2009

Yu Yingpu, Marintchev Assen, Kolupaeva Victoria G, Unbehaun Anett, Veryasova Tatyana, Lai Shao-Chiang, Hong Peng, Wagner Gerhard, Hellen Christopher U T, Pestova Tatyana V

Abstract excerpt

The universally conserved eukaryotic initiation factor (eIF), eIF1A, plays multiple roles throughout initiation: it stimulates eIF2/GTP/Met-tRNA(i)(Met) attachment to 40S ribosomal subunits, scanning, start codon selection and subunit joining. Its bacterial ortholog IF1 consists of an oligonucleotide/oligosaccharide-binding (OB) domain, whereas eIF1A additionally contains a helical subdomain, N-terminal tail...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19561193
DOI: 10.1093/nar/gkp519
PMCID: PMC2731904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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