Article
Translation initiation region dependency of translation initiation in Escherichia coli by IF1 and kasugamycin.
The FEBS journal - 1 Jun 2010
Surkov Serhiy, Nilsson Hanna, Rasmussen Louise C V, Sperling-Petersen Hans U, Isaksson Leif A
Abstract excerpt
Translation initiation factor 1 (IF1) is an essential protein in prokaryotes. The nature of IF1 interactions with the mRNA during translation initiation on the ribosome remains unclear, even though the factor has several known functions, one of them being RNA chaperone activity. In this study, we analyzed translational gene expression in vivo in two cold-sensitive chromosomal mutant variants of IF1 with amino...
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