Article
Functional analysis of the invariant residue G791 of Escherichia coli 16S rRNA.
Journal of microbiology (Seoul, Korea) - 1 Oct 2007
Song Woo-Seok, Kim Hong-Man, Kim Jae-Hong, Sim Se-Hoon, Ryou Sang-Mi, Kim Sanggoo, Cha Chang-Jun, Cunningham Philip R, Bae Jeehyeon, Lee Kangseok
Abstract excerpt
The nucleotide at position 791(G791) of E. coli 16S rRNA was previously identified as an invariant residue for ribosomal function. In order to characterize the functional role of G791, base substitutions were introduced at this position, and mutant ribosomes were analyzed with regard to their protein synthesis ability, via the use of a specialized ribosome system. These ribosomal RNA mutations attenuated the...
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