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Article

Role of 16S ribosomal RNA methylations in translation initiation in Escherichia coli.

The EMBO journal - 19 Mar 2008

Das Gautam, Thotala Dinesh Kumar, Kapoor Suman, Karunanithi Sheelarani, Thakur Suman S, Singh N Sadananda, Varshney Umesh

Abstract excerpt

Translation initiation from the ribosomal P-site is the specialty of the initiator tRNAs (tRNA(fMet)). Presence of the three consecutive G-C base pairs (G29-C41, G30-C40 and G31-C39) in their anticodon stems, a highly conserved feature of the initiator tRNAs across the three kingdoms of life, has been implicated in their preferential binding to the P-site. How this feature is exploited by ribosomes has remained...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18288206
DOI: 10.1038/emboj.2008.20
PMCID: PMC2274930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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