Article
The accuracy of statistical methods for estimation of haplotype frequencies: an example from the CD4 locus.
American journal of human genetics - 1 Aug 2000
Tishkoff S A, Pakstis A J, Ruano G, Kidd K K
Abstract excerpt
Haplotype analysis has become increasingly important for the study of human disease as well as for reconstruction of human population histories. Computer programs have been developed to estimate haplotype frequencies statistically from marker phenotypes in unrelated individuals. However, there currently are few empirical reports on the accuracy of statistical estimates that must infer linkage phase. We have...
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