Article
Haplotype uncertainty in association studies.
Genetic epidemiology - 1 May 2007
Mensah F K, Gilthorpe M S, Davies C F, Keen L J, Adamson P J, Roman E, Morgan G J, Bidwell J L, Law G R
Abstract excerpt
Inferring haplotypes from genotype data is commonly undertaken in population genetic association studies. Within such studies the importance of accounting for uncertainty in the inference of haplotypes is well recognised. We investigate the effectiveness of correcting for uncertainty using simple methods based on the output provided by the PHASE haplotype inference methodology. In case-control analyses...
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