Article
Understanding the accuracy of statistical haplotype inference with sequence data of known phase.
Genetic epidemiology - 1 Nov 2007
Andrés Aida M, Clark Andrew G, Shimmin Lawrence, Boerwinkle Eric, Sing Charles F, Hixson James E
Abstract excerpt
Statistical methods for haplotype inference from multi-site genotypes of unrelated individuals have important application in association studies and population genetics. Understanding the factors that affect the accuracy of this inference is important, but their assessment has been restricted by the limited availability of biological data with known phase. We created hybrid cell lines monosomic for human...
Topics
- Black or African American
- Algorithms
- Animals
- Cell Line
- Chromosomes, Human, Pair 19
- Female
- Genotype
- Humans
- Male
- Mice
- Sequence Analysis, DNA
- White People