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Article

Implication of the G2 checkpoint in the maintenance of genome integrity.

Pathologie-biologie - 1 Apr 2000

Piette J, Muñoz P

Abstract excerpt

Checkpoints are surveillance mechanisms that block cell cycle transitions, for instance in response to DNA damage. We summarise here recent progress in the molecular characterisation of the G2 checkpoint which controls the entry into mitosis, and review new evidence which implicates deregulated expression of checkpoint proteins and proteins involved in DNA damage repair in cancer development. There now exists...

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PMID: 10858951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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