Article
Differential expression of E-cadherin in lobular and ductal neoplasms of the breast and its biologic and diagnostic implications.
American journal of clinical pathology - 1 Jan 2001
Acs G, Lawton T J, Rebbeck T R, LiVolsi V A, Zhang P J
Abstract excerpt
We studied the pattern of E-cadherin expression in 183 invasive carcinomas (100 ductal, 42 lobular, 41 with mixed ductal and lobular features) and 198 in situ carcinomas (131 ductal, 53 lobular, 14 in situ with ductal and lobular features) by immunohistochemistry. We found a highly significant correlation of E-cadherin membrane expression with the histologic phenotype of the tumors. While moderate to strong...
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