Article
Differential patterns of allelic loss in estrogen receptor-positive infiltrating lobular and ductal breast cancer.
Genes, chromosomes & cancer - 1 Dec 2008
Loo L W M, Ton C, Wang Y-W, Grove D I, Bouzek H, Vartanian N, Lin M-G, Yuan X, Lawton T L, Daling J R, Malone K E, Li C I, Hsu L, Porter P L
Abstract excerpt
The two main histological types of infiltrating breast cancer, lobular (ILC) and the more common ductal (IDC) carcinoma are morphologically and clinically distinct. To assess the molecular alterations associated with these breast cancer subtypes, we conducted a whole-genome study of 166 archival estrogen receptor (ER)-positive tumors (89 IDC and 77 ILC) using the Affymetrix GeneChip(R) Mapping 10K Array to...
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