Article
Sex-specific trans-regulatory variation on the Drosophila melanogaster X chromosome.
PLoS genetics - 1 Feb 2015
Stocks Michael, Dean Rebecca, Rogell Björn, Friberg Urban
Abstract excerpt
The X chromosome constitutes a unique genomic environment because it is present in one copy in males, but two copies in females. This simple fact has motivated several theoretical predictions with respect to how standing genetic variation on the X chromosome should differ from the autosomes. Unmasked expression of deleterious mutations in males and a lower census size are expected to reduce variation, while...
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