Article
The loss of estrogen and progesterone receptor gene expression in human breast cancer.
Journal of mammary gland biology and neoplasia - 1 Jan 1998
Lapidus R G, Nass S J, Davidson N E
Abstract excerpt
Hormone responsiveness is a critical determinant of breast cancer progression and management, and the response to endocrine therapy is highly correlated with the estrogen receptor (ER)3 and progesterone receptor (PR) status of tumor cells. Thus, key areas of study in breast cancer are those mechanisms that regulate ER and PR expression in normal and malignant breast tissues. One-third of all breast cancers lack...
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