Mechanisms of hormone resistance in breast cancer.

doi:10.1007/BF00689685

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Article

Mechanisms of hormone resistance in breast cancer.

Breast cancer research and treatment - 1 Jan 1993

Horwitz K B

Abstract excerpt

At least half of all advanced breast cancers are positive for estrogen receptor (ER) and progesterone receptor (PR), but many nevertheless fail to respond to endocrine therapy. Studies of breast cancer cell lines and breast tumor specimens are beginning to reveal molecular heterogeneity of the re...

Topics

Amino Acid Sequence
Breast Neoplasms
Cell Division
Drug Resistance
Female
Humans
Molecular Sequence Data
Mutation
Progestins
Receptors, Estrogen
Receptors, Progesterone
Tamoxifen
Tumor Cells, Cultured

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