Article
Angiogenic squamous dysplasia in bronchi of individuals at high risk for lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2000
Keith R L, Miller Y E, Gemmill R M, Drabkin H A, Dempsey E C, Kennedy T C, Prindiville S, Franklin W A
Abstract excerpt
Lung carcinogenesis is assumed to be a multistep process, but detailed understanding of the sequential morphological and molecular changes preceding invasive lung cancer remains elusive. To better understand early lung carcinogenesis, we initiated a program of fluorescence bronchoscopy in smokers at high risk for lung cancer. In the bronchial biopsies from these subjects, we observed a unique lesion consisting of...
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