Article
Angiogenesis of lung cancer utilizes existing blood vessels rather than developing new vessels using signals from carcinogenesis.
Anticancer research - 1 May 2013
Uramoto Hidetaka, Yamada Sohsuke, Tanaka Fumihiro
Abstract excerpt
Cancer cells metastasize via angiogenesis and are a long-standing therapeutic target in malignant tumors. Vascular endothelial growth factor (VEGF) antibodies have been developed for clinical use, with limited benefits. Therefore, identifying the underlying mechanisms of angiogenesis regarding whether tumor vessels are derived from cancer cells or blood vessels in existence, is highly anticipated. Recently,...
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