Article
Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease.
Human molecular genetics - 22 May 2000
Cho J H, Nicolae D L, Ramos R, Fields C T, Rabenau K, Corradino S, Brant S R, Espinosa R, LeBeau M, Hanauer S B, Bodzin J, Bonen D K
Abstract excerpt
The idiopathic inflammatory bowel diseases (IBDs), consisting of Crohn's disease and ulcerative colitis, are complex genetic disorders involving chronic inflammation of the intestines. Multiple genetic loci have been implicated through genome-wide searches, but refinement of localization sufficient to undertake positional cloning efforts has been problematic. This difficulty can be obviated through identification...
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