Article
Refinement in localization and identification of gene regions associated with Crohn disease.
American journal of human genetics - 10 Jan 2013
Elding Heather, Lau Winston, Swallow Dallas M, Maniatis Nikolas
Abstract excerpt
The risk of Crohn disease (CD) has a large genetic component. A recent meta-analysis of 6 genome-wide association studies reported 71 chromosomal intervals but does not account for all of the known genetic contribution. Here, we refine localization of the previously reported intervals and also identify additional CD susceptibility genes using a mapping approach that localizes causal variants based on genetic maps...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
