Article
The fusion protein MEN 11303 (granulocyte-macrophage colony stimulating factor/erythropoietin) acts as a potent inducer of erythropoiesis.
Experimental hematology - 1 May 2000
Battaglia A, Fattorossi A, Pierelli L, Bonanno G, Marone M, Ranelletti F O, Coscarella A, De Santis R, Bach S, Mancuso S, Scambia G
Abstract excerpt
OBJECTIVE: A fusion protein made of human granulocyte-macrophage colony-stimulating factor (GM-CSF) and erythropoietin (EPO), referred to as MEN 11303, has been tested for biologic activity using mobilized CD34(+) cells. METHODS AND RESULTS: MEN 11303 and a combination of GM-CSF/EPO produced the same amount of colony-forming unit granulocyte-macrophage (CFU-GM), of burst-forming unit erythroid (BFU-E), and of...
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