Article
Comparative effects of insulin-like growth factor II (IGF-II) and IGF-II mutants specific for IGF-II/CIM6-P or IGF-I receptors on in vitro hematopoiesis.
Stem cells (Dayton, Ohio) - 1 May 1996
Schwartz G N, Warren M K, Sakano K, Szabo J M, Kessler S W, Pashapour A, Gress R E, Perdue J F
Abstract excerpt
This report presents the results of studies investigating the effect of insulin-like growth factor II (IGF-II) on the proliferation and differentiation of CD34+ bone marrow cells in serum-substituted liquid cultures. Bone marrow cells were enriched for CD34+ cells and then placed in liquid cultur...
Topics
- Antigens, CD34
- Bone Marrow Cells
- Cadaver
- Cell Count
- Cell Differentiation
- Cell Division
- Culture Media
- Hematopoiesis
- Hematopoietic Stem Cells
- Humans
- Insulin-Like Growth Factor II
- Interleukin-3
- Megakaryocytes
- Mutation
- Receptor, IGF Type 1