Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Typing of multiple single-nucleotide polymorphisms by a microsphere-based rolling circle amplification assay.

Analytical chemistry - 1 Dec 2007

Li Jishan, Zhong Wenwan

Abstract excerpt

The combination of suspension array with rolling circle amplification can lead to a sensitive and specific assay for single-nucleotide polymorphisms (SNPs) detection, as demonstrated in this study. A circular template generated by ligation upon the recognition of a point mutation on DNA targets was amplified isothermally by the Phi29 polymerase on microspheres. The elongation products were labeled with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line, Tumor
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Flow Cytometry

Share to Microspheres

Share to Point Mutation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 17973502
DOI: 10.1021/ac701702t

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Typing of multiple single-nucleotide polymorphisms by a microsphere-based rolling circle amplification assay.PMID 17973502Read ↗

Homogeneous and label-free fluorescence detection of single-nucleotide polymorphism using target-primed branched rolling circle amplification.Semantic proximity Read ↗

Rolling circle amplification combined with gold nanoparticle aggregates for highly sensitive identification of single-nucleotide polymorphisms.Semantic proximity Read ↗

Ligation-mediated rolling-circle amplification-based approaches to single nucleotide polymorphism detection.Semantic proximity Read ↗

Suspension arrays for high throughput, multiplexed single nucleotide polymorphism genotyping.Semantic proximity Read ↗

Mutation detection and single-molecule counting using isothermal rolling-circle amplification.Semantic proximity Read ↗

Fluorescent microsphere-based readout technology for multiplexed human single nucleotide polymorphism analysis and bacterial identification.Semantic proximity Read ↗

A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension.Semantic proximity Read ↗

Multiplexed SNP genotyping using primer single-base extension (SBE) and microsphere arrays.Semantic proximity Read ↗

Rolling-circle amplification in DNA diagnostics: the power of simplicity.Semantic proximity Read ↗

Novel and alternate SNP and genetic technologies.Semantic proximity Read ↗

Novel biosensing methodologies for improving the detection of single nucleotide polymorphism.Semantic proximity Read ↗

Single Nucleotide Recognition and Mutation Site Sequencing Based on a Barcode Assay and Rolling Circle Amplification.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.